A machine would do the job of the liver, much like dialysis helps when the kidneys stop working. There are many different types of devices being studied. Research suggests that some, but not all, devices may improve A well-controlled multicenter trial showed that one system, called an extracorporeal liver support system, helped people with acute liver failure survive without a transplant. The treatment is also called high-volume plasma exchange. Transplanting only the cells of the liver — not the entire organ — may temporarily delay the need for a liver transplant. In some cases, it could lead to a complete recovery. A shortage of good-quality donor livers has limited the use of this treatment. This type of transplant replaces the human liver with one from a nonhuman animal source. Doctors performed experimental liver transplants using pig livers several decades ago, but results were disappointing. However, advancements in immune and transplant medicine have prompted researchers to consider this treatment again. It may help provide support for those waiting for a human liver transplant.

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