Leptin is the hormone that controls appetite that is produced by fat cells in the body. The lens sends signals to the brain that the body is full. It reduces the appetite and stimulates the metabolism, making a person feel satisfied. Discover the list of foods that increase sensitivity to leptin naturally. Also known as the satiety hormone, it curbs your appetite when you have enough energy to meet your body's needs. The hormone derives its name from the Greek word 'leptos', which means thin. The normal functioning of leptin ensures efficient metabolic function, brain performance, regulation of mood, memory and coordination.